This study was devised to observe the inhibitory effect of 7 kinds of the acidic polysaccharide fraction(PG_1, PG_2, PG_3, PG_4, PC_5, PG_6 and PG_7) from Korean white ginseng on a lipolytic action of Toxohormone-L.
Toxohormone-L is a lipolytic factor, found in ascites fluid of sarcoma -180 bearing mice and of patients with hepatoma. A substace that inhibited the lipolytic action of Toxohormone-L was isolated from white ginseng powder. This substance was an acidic polysaccharides.
In vitro test showed that the inhibitory effect of PG_5 fraction of the lipolysis by Toxohormone-L was highest percent among other treatments at concentration of 50, 10, 200, 500 and l,000㎍/㎖ of reaction mixture. And total inhibitory activity (units) of PG_1 and PG_4 was highest among other treatments at the same concentration and that of 10㎍/㎖.
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